Dynamic fixers
The 2015 Nobel Prize in Chemistry has been awarded to the three fathers of the DNA damage field, Swedish scientist Tomas Lindahl, American scientist Paul Modrich and US-Turkish scientist Aziz Sancar, for their seminal work in the DNA repair field during the 1970s – 1980s.
Collectively, they defined that organisms are able to survive at all because they have very specialised processes involving cascades of enzymes which detect DNA damage and perform a triage-like step-by-step repair.
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