10/23/2015
10/16/2015
Dynamic fixers
The 2015 Nobel Prize in Chemistry has been awarded to the three fathers of the DNA damage field, Swedish scientist Tomas Lindahl, American scientist Paul Modrich and US-Turkish scientist Aziz Sancar, for their seminal work in the DNA repair field during the 1970s – 1980s.
Collectively, they defined that organisms are able to survive at all because they have very specialised processes involving cascades of enzymes which detect DNA damage and perform a triage-like step-by-step repair.
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